The Nature of Irreversible Shock

The problem of irreversible shock.

The term ' shock' was first used by the French surgeon, Le Dran, in 1743 when describing the effects of gunshot wounds; however, he used this term to describe the act of collision of a missile with the body rather than the resulting functional damage. Between the i8th and 20th centuries the meaning of this term has gradually altered until now it is used to describe a syndrome , one of the main ...

the myocardial factor in irreversible hemorrhagic shock: alterations of myocardial performance of the isolated canineheart preparation following irreversible hemorrhagic shock

myocardial performance, utilizing the isolated canine heart preparation, was studied in two groups: normal control dogs and those subjected to hemorrhagic shock. a marked deterioration in myocardial functional capacity was observed in the shock group. from this study, myocardial incapacity resulting from the period of acute hypotension is felt to be a contributing factor in the death of animals...

Effect of hypothermia in irreversible hemorrhagic shock.

Irreversible hemorrhagic shock was studied in normothermic dogs and in dogs subjected to hypothermia at three different periods following the onset of the hemorrhage. A significant prolongation of life was observed in the hypothermic dogs, the increase in survival time being greatest in those dogs cooled early in the shock sequence. The temperature, pulse, respiration, blood pressure, electroca...

Irreversible Hemorrhagic Shock in Germfree Rats

Evidence has been provided that a state of irreversible hemorrhagic shock can be induced in a bacteria-free environment in rats reared under germfree conditions. The response to bleeding, the duration of the hypotensive episode and the pathological changes were the same in the germfree and in normal stock rats. The findings are interpreted as evidence opposed to the concept that bacteria or bac...

The Nature and Management of Electric Shock.